Our federally-funded lab studies the cellular and molecular basis of behavior and disease. We are seeking applicants for our doctoral program to study the pathophysiology of Duchenne muscular dystrophy (DMD). The project involves the use of humanized nematode models, and human cell cultures. Active areas of study in this project include:
A) Early pathophysiology of DMD
B) Neurological effects and mechanisms of DMD
C) Patient-specific humanized nematode-to-human cell culture models of DMD
D) Role of dystrophin isoforms in normal and altered muscle plasticity
The project involves the use of cutting-edge techniques including: Calcium ratiometry, electrophysiology, immunohistochemistry, advanced cloning, RNAi, qPCR, CRISPR/Cas9, transgenesis, in depth behavioral and kinematic analysis, confocal microscopy, automated long term screening, and more.
You would be joining a multiple award-winning team* of vibrant and diverse scientists including high school interns, undergrad, MS, PhD, and Postdoctoral researchers. There are many opportunities for networking and collaborations both within and outside our institution.
Our average PhD student graduates in 5 years with 4 first author peer-reviewed manuscripts in journals that include PNAS and eLife.
The Vidal-Gadea Lab's home at Illinois State University is located in central Illinois. We are close to several metropolitan areas and travel hubs. Our stipends are competitive ($27,000/year) and the cost of living in our area is quite affordable (e.g. housing costs are 66.5% that of the national average).
We are looking for driven, experienced applicants with previous research experience to join our lab in Spring or Fall of 2022.
*Awards received by our team in the past five years include:
- 2021 Illinois State University's Million Dollar Club Award
- 2021 Louis Stokes Alliance for Minority Participation's Faculty Mentor Award
- 2020 Illinois Science and Technology Coalition Researchers to Know Award
- 2019 Illinois State University's Research Initiative Award
- 2018 McLean County Chamber of Commerce Outstanding STEM Professional
- 2018 Louis Stokes Alliance for Minority Participation's Faculty Mentor Award.
The ideal candidate will be a driven and experienced researcher with a demonstrated trajectory (e.g. abstracts, talks, or publications). Nematode or human cell culture experience would be assets but are not required.
Additional Salary Information: Funding is provided through a combination of RAs and TAs.
About Illinois State University
We are a research lab focusing on the molecular basis of behavior and disease using the nematode C. elegans, human cell culture, and crustaceans. We are based at Illinois State University.